Heparin-bonded Dacron or polytetrafluoroethylene for femoropopliteal bypass grafting: A multicenter trial
Identifieur interne : 009F10 ( Main/Exploration ); précédent : 009F09; suivant : 009F11Heparin-bonded Dacron or polytetrafluoroethylene for femoropopliteal bypass grafting: A multicenter trial
Auteurs : Carol Devine [Royaume-Uni] ; Ba Hons [Royaume-Uni] ; Charles Mccollum [Royaume-Uni]Source :
- Journal of Vascular Surgery [ 0741-5214 ] ; 2001.
Abstract
Background: Dacron (polyester fiber) was largely abandoned for femoropopliteal bypass grafts 30 years ago because saphenous vein achieved better patencies. However, in patients taking aspirin, patency in above-knee femoropopliteal bypass grafts has recently been shown to be equivalent to that with saphenous vein. We compared heparin-bonded Dacron (HBD) and polytetrafluoroethylene (PTFE) in a randomized multicenter trial including below-knee popliteal or tibioperoneal trunk bypass graft where the long saphenous vein was absent or inadequate. Methods: Over 28 months, 209 patients undergoing femoropopliteal bypass grafts (180 above-knee, 29 below-knee) were randomized to HBD (n = 106) or PTFE (n = 103). Each patient was given aspirin (300 mg/d) before surgery, and this continued unless the patient had intolerance to the aspirin. Results: The mean follow-up was 42 months (range, 28-55). Fifteen (7.1%) patients died with patent grafts, and three (1.4%) infected grafts were removed. Patency (measured with Kaplan-Meier survival analysis) at 1, 2, and 3 years for HBD was 70%, 63%, and 55% compared with 56%, 46%, and 42%, respectively, for PTFE (P =.044). A total of 67 secondary interventions were performed on 48 thrombosed grafts; long-term patency was achieved in only three. Risk factors for arterial disease did not significantly influence patency. Amputations have been performed in 23 patients, six after HBD and 17 after PTFE bypass grafts (P =.015). Conclusions: HBD achieved better patency than PTFE, which carried a high risk of subsequent amputation. (J Vasc Surg 2001;33:533-9.)
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DOI: 10.1067/mva.2001.113578
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<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Heparin-bonded Dacron or polytetrafluoroethylene for femoropopliteal bypass grafting: A multicenter trial</title><author><name sortKey="Devine, Carol" sort="Devine, Carol" uniqKey="Devine C" first="Carol" last="Devine">Carol Devine</name></author><author><name sortKey="Hons, Ba" sort="Hons, Ba" uniqKey="Hons B" first="Ba" last="Hons">Ba Hons</name></author><author><name sortKey="Mccollum, Charles" sort="Mccollum, Charles" uniqKey="Mccollum C" first="Charles" last="Mccollum">Charles Mccollum</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:BDA3067742E82F2B63F724F14D558E2130C262CF</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1067/mva.2001.113578</idno><idno type="url">https://api.istex.fr/document/BDA3067742E82F2B63F724F14D558E2130C262CF/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">005925</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">005925</idno><idno type="wicri:Area/Istex/Curation">005925</idno><idno type="wicri:Area/Istex/Checkpoint">002C14</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">002C14</idno><idno type="wicri:doubleKey">0741-5214:2001:Devine C:heparin:bonded:dacron</idno><idno type="wicri:Area/Main/Merge">00A364</idno><idno type="wicri:Area/Main/Curation">009F10</idno><idno type="wicri:Area/Main/Exploration">009F10</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Heparin-bonded Dacron or polytetrafluoroethylene for femoropopliteal bypass grafting: A multicenter trial</title><author><name sortKey="Devine, Carol" sort="Devine, Carol" uniqKey="Devine C" first="Carol" last="Devine">Carol Devine</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>South Manchester University Hospital, Department of Surgery. Manchester</wicri:regionArea><wicri:noRegion>Department of Surgery. Manchester</wicri:noRegion></affiliation></author><author><name sortKey="Hons, Ba" sort="Hons, Ba" uniqKey="Hons B" first="Ba" last="Hons">Ba Hons</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>South Manchester University Hospital, Department of Surgery. Manchester</wicri:regionArea><wicri:noRegion>Department of Surgery. Manchester</wicri:noRegion></affiliation></author><author><name sortKey="Mccollum, Charles" sort="Mccollum, Charles" uniqKey="Mccollum C" first="Charles" last="Mccollum">Charles Mccollum</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>South Manchester University Hospital, Department of Surgery. Manchester</wicri:regionArea><wicri:noRegion>Department of Surgery. Manchester</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Vascular Surgery</title><title level="j" type="abbrev">YMVA</title><idno type="ISSN">0741-5214</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2001">2001</date><biblScope unit="volume">33</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="533">533</biblScope><biblScope unit="page" to="539">539</biblScope></imprint><idno type="ISSN">0741-5214</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0741-5214</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background: Dacron (polyester fiber) was largely abandoned for femoropopliteal bypass grafts 30 years ago because saphenous vein achieved better patencies. However, in patients taking aspirin, patency in above-knee femoropopliteal bypass grafts has recently been shown to be equivalent to that with saphenous vein. We compared heparin-bonded Dacron (HBD) and polytetrafluoroethylene (PTFE) in a randomized multicenter trial including below-knee popliteal or tibioperoneal trunk bypass graft where the long saphenous vein was absent or inadequate. Methods: Over 28 months, 209 patients undergoing femoropopliteal bypass grafts (180 above-knee, 29 below-knee) were randomized to HBD (n = 106) or PTFE (n = 103). Each patient was given aspirin (300 mg/d) before surgery, and this continued unless the patient had intolerance to the aspirin. Results: The mean follow-up was 42 months (range, 28-55). Fifteen (7.1%) patients died with patent grafts, and three (1.4%) infected grafts were removed. Patency (measured with Kaplan-Meier survival analysis) at 1, 2, and 3 years for HBD was 70%, 63%, and 55% compared with 56%, 46%, and 42%, respectively, for PTFE (P =.044). A total of 67 secondary interventions were performed on 48 thrombosed grafts; long-term patency was achieved in only three. Risk factors for arterial disease did not significantly influence patency. Amputations have been performed in 23 patients, six after HBD and 17 after PTFE bypass grafts (P =.015). Conclusions: HBD achieved better patency than PTFE, which carried a high risk of subsequent amputation. (J Vasc Surg 2001;33:533-9.)</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Devine, Carol" sort="Devine, Carol" uniqKey="Devine C" first="Carol" last="Devine">Carol Devine</name></noRegion><name sortKey="Hons, Ba" sort="Hons, Ba" uniqKey="Hons B" first="Ba" last="Hons">Ba Hons</name><name sortKey="Mccollum, Charles" sort="Mccollum, Charles" uniqKey="Mccollum C" first="Charles" last="Mccollum">Charles Mccollum</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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